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General Precautions: Vitamin B12 deficiency that is allowed to progress for longer than 3 months may produce permanent degenerative lesions of the spinal cord

5 B12 Shots Work Quickly A response is usually seen within 48 to 72 hours, with brisk production of new red blood cells

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If you follow a plant-based or vegan diet, you might need to get B12 from fortified foods or supplements